Far Infrared Acupuncture Patch” — non-invasive, environmental-friendly, innovative tool to Assist Acupuncture for Analgesic and Anti-inflammatory Effects

Dr. Rosita Alex Li
(Guangzhou University of Traditional Chinese Medicine, Xyber Force Technology Co., Ltd.,
30E Legend Tower, 7 Shing Yip Street, Kwun Tong, Kowloon, Hong Kong)

Abstract:

Background and Objective: The analgesic and anti-inflammatory effect of acupuncture has been widely recognised by the academic community, Professor Li Wanzi’s breakthrough invention—“Far Infrared Acupuncture Patch”—an auxiliary acupuncture tool, effectively emits an average of 90% far infrared rays (FIR), provides a non-invasive and environmentally friendly solution to analgesic and anti-inflammatory purposes.

Materials and methods: To prove that the traditional acupuncture work through the body surface as physical stimulation, inducing a series of biological information which cause the local tissue to release adenosine, greatly increase the levels of adenosine monophosphate (AMP), actively participate to the neuroimmunomodulatory axis, lead to anti-inflammation in the local tissue, reduce the release of pain signals from neurones. To further prove that FIR can stimulate mitochondrion and lead to the generation of adenosine triphosphate (ATP), inducing cell repair and tissue healing, meanwhile increase the transmission of nitric oxide which could increase blood volume and motivate the body’s immune functions. Finally, through three verification methods to prove that the invention of the “Far Infrared Acupuncture Patch” can be used as a tool to assist acupuncture: (1) since 2013 by a number of international scientific certification has been granted to confirm the “Far Infrared Acupuncture Patch” effectively emits an average of more than 90% far infrared rays; (2) the clinical evidence demonstrated by a traditional Chinese acupuncturists that the patch had quickly deliver analgesic effects to the patient; (3) In 2013, a Double-Blind Randomized Trial was performed with 281 people, the test results showed that 15 minutes after the application of the patch effectively relieve pain for 61% patients and 81% patients felt the pain relieved after 1 hour.

Conclusion: The invention of the “Far Infrared Acupuncture Patch”  is non-invasive, without using drug, electricity, or additional material (very environmentally friendly), and capable to release an average of more than 90% far infrared rays to deliver sequence re-aligned bioinformation to the brain to initiate self-healing, which complement to the mechanism of acupuncture. Chinese medicine practitioners can use their professional guidance to locate “key acu-points” and then use the “Far Infrared Acupuncture Patch” instead of silver needles to continue the treatment. There would not be any activity restrictions and diet taboo, not only to assist the treatment process of acupuncture but to promote the efficacy of analgesia and anti-inflammation to shorten suffering of the patients, also break their fear of acupuncture. “Far Infrared Acupuncture Patch” is an innovative tool to assist and enhance acupuncture skills.

Keywords: acupuncture, far infrared therapy, chronic pain analgesia, Cell repair, anti-inflammation

1 Introduction
The analgesic and anti-inflammatory effect of acupuncture has been widely recognised by the academic and medical community1. To promote the integration of Chinese and Western medicine, advocating innovative technology with traditional acupuncture skills is a dream of every medical, academic and technological leader to the contribution to the general well-being of human. As early as ten years ago, Honourable Professor Jin Guanyuan from Guangzhou University of Chinese Medicine used a systematic approach known as “cybernetics” to review physiology, pathology and the acupuncture treatment process simultaneously under the same framework. Last year, Professor Jin published an article in the journal namely “Guide to Traditional Chinese Medicine” about his view on driving modern acupuncture medicine to a new peak. He mentioned the need for advanced theoretical support and scientific research hardware that meets the international standards2. Base on the concept of acupuncture therapy, Professor Li Wanzi from Guangzhou University of Chinese Medicine and her research team dedicated their studies in Bioinformatics and Far Infrared Rays (FIR) technology since 1998. Driven by the strong desire to further develop and inherit Chinese medicine, we not only succeeded in combining these two top-notch technologies, but also developed a groundbreaking invention: a far infrared acupuncture patch containing “sequence re-alignment” bioinformation and 90% far infrared in the size of a stamp. Without invasion (topical application without needling) and environmental friendly (without medicine nor electricity nor substances), this innovative technology can transfer bioinformation and far infrared rays to the human body. By placing the “Far Infrared Acupuncture Patch” on the correct acu-points, the patch can instantly activate the human nerve fibres and neurons to transmit bioinformation to the spine and brain. The excited central nervous system (CNS) releases hormones that induce cell repair, renewal and reconstruction, hence, the meridian passage is clear, and the energised “Qi” and blood circulation can relieve pain, also enhancing the body’s basic physiological functions3.

2 Breakthrough analgesic and anti-inflammatory measures in acupuncture and far infrared rays treatment
The therapeutic effect of acupuncture is known as a reflex to the physical stimulation of the needle at a specific point on the skin, in which controlling the transmission of the reflected information, excluding additional information processing and interference can improve the result, as well as its repeatability4. In view of the above coupling mechanism, there are recent reports showing a series of biosignalling cascades induced by acupuncture, similar to the regulatory role of the nervous system in the occurrence and development of inflammation. The most representative argument is acupuncture creates a micro trauma on the skin which acts as a stimulus to the local tissue to release adenosine, results in an elevation of adenosine monophosphate (AMP) concentration, causing anti-inflammatory effects in that area, and hence sending less pain signal to the brain5. The above findings fully validate the “Neuroendocrine Immunomodulation (NIM)” theory of neurological systems, also echo to the ground to our inventions, i.e. to effectively use FIR to initiate sequence re-aligned bioinformation signal transmission to the CNS, via various NIM pathways to induce cell repair, renewal, and reconstruction, achieving the purpose of controlling tissue inflammation and relieve pain. “FIR acupuncture patch” improves the acupuncture reflex information transmission which could be processed and interfered, it is non-invasive which means those patients that are afraid of needling could enjoy the benefit of acupuncture brought by our 6000 years of clinical experiences, thus we propose “FIR acupuncture patch” is an innovative and reliable tool to assist and enhance acupuncture therapy.

3 The analgesic and anti-inflammatory mechanism of far-infrared rays treatment
FIR is an electromagnetic wave which wavelength is between 5.6-1000μm, only the band 6-14μm is closely related to the growth and development of all organisms, known as the “growth ray”. The growth ray is most commonly used clinically to treat open wounds, pain relief, high blood pressure, stress, poor sleeping quality, high blood sugar, fatigue, malignant tumour, maternal urine retention, paediatric colonic spasm and so on. FIR emission rate must reach 90% or more in order to be qualified for therapeutic use; only this level of energy or higher can penetrate through our clothes and skin to reach the targeted cells, creating a “resonance” phenomenon: Vibrational Transition and Rotational Transition6. If applied on the acu-point, the thermal effect and non-thermal effect of FIR can increase the electrical conductivity of the acupuncture point7, meanwhile strengthen the sympathetic nerve activity and enhance the regulation between the parasympathetic and sympathetic nervous systems, leading to microvascular dilation, increase vascular elasticity and ultimately enhance the blood circulation, accelerating the treatment and reach the goal of the therapy8.

To further understand the biophysical mechanism of FIR therapy, we could pay attention to two aspects, the mitochondrion and nitric oxide (NO). Scholars speculate that “Qi” is a property of mitochondrion, and the human meridian and acu-points are tissues made up with cells that have more mitochondria9,10. A mitochondrion consists of two layers of membranes, a smooth outer membrane and an inner membrane which is inward-folding like ridges; a cavity between the two layers and the central part of the cell is a matrix. The matrix contains all the enzymes required for the tricarboxylic acid cycle in metabolism, whereas the inner membrane contains ATPases and accommodates the respiratory chain enzyme system. These circulatory systems not only control oxygen and glucose metabolism, but also control the supply of energy to promote any cell activity. Scientists have confirmed the importance of mitochondria in blood supply and neural transmission by altering the gene expression of mitochondrial chloride channels (CLIC4) and protein kinases in animal cerebral ischemia model11,12. These findings correspond to Professor Xu Nenggui’s early publications about a proposed regulatory model of acupuncture by means of a rat focal cerebral ischemia model13. In case of chemotherapy, we learned that mitochondria are very sensitive to light energy, and that many patients have a neuropathic phenotype that is positively correlated with mitochondrial dysfunction. Regarding the action mechanism, researchers derived that mitochondrial dysfunction could lead to a decrease in the production of adenosine triphosphate (ATP), and hence the reduced polarity at the ATP-sensitive K+ channels attenuates the activities of the sensory neurons, encouraging the transmissions of pain signals to the brain14,15. In other words, once the acu-point is stimulated by intensive FIR, the intracellular mitochondria will be excited and then produce a large number of ATPases to promote ATP synthesis. High ATP levels increase the action potential of neurons, the increased polarity weakens the pain signalling activity but activates a number of molecular activities, such as cell differentiation, bioinformation transmission and apoptosis16,17. In conclusion, FIR can stimulate mitochondrial activities and lead to ATP generation, high ATP levels promote cell repair and tissue healing to assist acupuncture therapy. Tissue regeneration requires a lot of energy and nutrition, thus blood flow plays a key role in supporting immune function.

The other benefit of FIR is to stimulate NO activities. NO is a biologically-active gas molecule that acts as an important messenger molecule between cells, also known as a neurotransmitter18. It is involved in many physiological processes and cellular activities, such as cell signalling, nerve repair, pain modulation, blood circulation, immune stress response etc., inadequate or excessive NO levels are harmful to the human body (see figure 1). Animal inflammatory pain model can mimic clinical inflammatory induced pain. In the past two decades, advance in molecular biology technology gives scientists a better understanding of the role of NO in inflammatory pain and the mechanism behind its activity, such as its strength, the active site, the half-life, the genotype19. This information refines the “Qi” theory and supports it by a more systematic and quantitative research background, giving us a new perspective to study Chinese medicine and relevant clinical cases as our scientific background in FIR research. When we try to compare the effect of FIR stimulation to acupuncture in NO synthesis, the first common point is that both practices lead to vasodilation that cause an increase in blood flow, and then enhance oxygen and ATP supply, promote nutrition and growth factor transport to restore the body’s self-healing ability, reduce inflammation and pain20,21,22. Secondly, FIR induces NO release from the haemoglobin, promotes macrophage-mediated immune function, and increases the level of calmodulin cells for cell repair and regeneration at the damaged parts of the body, which is consistent to the effect of acupuncture23, 24. Thus, we conclude that the key to the therapeutic effect of both FIR and acupuncture therapy is about the control of gene expression of the proteins that is involved in the pain mechanism.

(Figure 1) The physiological role of nitric oxide

4 breakthrough invention ─ “Far Infrared Acupuncture Patch”
From the above evidences, acupuncture has analgesic and anti-inflammatory effects; far infrared rays also has the same analgesic and anti-inflammatory effects; as long as a tool can release 90% or more of far-infrared rays, it can be an auxiliary acupuncture tool (see figure 2). In November 2014, Dr. Li Wanzi publicised her study at WFAS in Houston which title was “bioinformation therapy – the most effective and not invasive treatment in the 21st century of acupuncture”3. In her paper, she described the treatment process of a Chinese medical practitioner using a far infrared acupuncture patch that contained FIR and bioinformation instead of silver needles to stimulate the acu-points, resulted in an instant pain relief on the patient’s right knee and his mobility was restored, proved that the in vivo and ex-vivo far-infrared rays has the function of information transmission, if the same emission rate is reached, these biologically photon-dispersed electromagnetic waves of the same molecular structure and same molecular structure will resonate and initiate a series of cell activities. In this case, the Chinese doctor placed the patches at the following acu-points: SP-10, Liv-7, Liv-8, SP-9, and St-35. Five minutes later, the doctor inspected that the patient’s pulse became even, more powerful, and not so fast; muscle relaxation was examined at the acu-points near the injured area. The patient reported much pain relieved, and was capable to bend his knees and walk properly. The quick restoration of physical activity confirmed that the human body is a perfect self-regulating open system, and the result of its interaction with external media is not only about the exchange of organic matters and energy, but also includes an exchange of bioinformation25. The patient reported much pain relieved, and was capable to bend his knees and walk properly. The quick restoration of physical activity confirmed that the human body is a perfect self-regulating open system, and the result of its interaction with external media is not only about the exchange of organic matters and energy, but also includes an exchange of bioinformation25. In September 2015, Prof. Li Wanzi published a clinical trial report entitled “Integrative Chinese and Western Medicine – Acupuncture Combined with Bioinformatics Medicine – Creating an Effective & Non-Invasive Acupuncture Treatment” at WFAS 201526. The actual number of patients involved in the clinical trial was 281, we adopted the double-blind randomised method to test whether the “pain relief patch” and the “strong knee pain relief patch” from the “pain relief series” of the “FIR acupuncture patch”, could instantaneous relief pain in two periods: (1) after 15 minutes; (2) after 1 hour. The test results showed that the patient’s pain was effectively relieved by up to 61% 15 minutes after the application of the “FIR acupuncture patch”, and the relief of pain was effectively increased to 81% 1 hour after the application.

Summarising the mechanism of the analgesic effect of far infrared rays and the therapeutic effects of needling acu-points over thousands of generations, as well as our past six years of clinical evidences, the bioinformation carried by the “FIR Acupuncture patch” invented by the scientists from the Xyber Force Techonology team could create new bioelectromagnetic field for the injured tissue. Different states of movement of the micro-matter are shown in the altered electromagnetic waves due to the signals from the re-aligned sequences of bioinformation, influencing the amino acid pattern, protein synthesis and cellular responses, ultimately improved the condition of the tissue and its function. Therefore, we should pay great attention to the scientific research of bioinformatics, not only to find out the reasons by the errors during signal transmission, but also to seek for the scientific method to correct these errors.

(Figure 2.) The “FIR Acupuncture Patch” emits over 90% far infrared rays can assist acupuncture to give effective analgesic and anti-inflammatory results.

In the past, scientists from different countries undergoing bioinformatics research have already found many methods to correct abnormal gene expressions, and the bio-waves emitted by the cells, but most of them use an external ultra-micro electromagnetic wave processor for detection and regulation of bio-waves. Our team has gone beyond this field. The correction no longer requires electricity, but through over 90% FIR to deliver the corrected, sequence re-aligned bioinformation to the brain. When the brain receives the new signals and analyses the correction, it will immediately respond by initiating the self-repair mechanism, which is similar to the neuronal reaction occurred during acupuncture. The impressive results of our “FIR Acupuncture Patches” also confirmed that it can be a great therapeutic tool to the Chinese doctors anytime and anywhere. The patient has no restrictions on activities and food taboos while using these non-invasive patches, showing a bioinformation technology breakthrough in this invention. To conclude, the clinical experiences of Chinese doctors help to instruct the rehabilitation through key acu-points, further stimulation can be done by our “FIR Acupuncture Patches” which will send corrected bioinformation directly to the brain, fully utilise the great ancient Chinese medicine. Our patches are non-invasive, without using drug, electricity, or additional material (very environmentally friendly), and our technology can be evaluated and certified by different institutions internationally. We were appointed to establish the “International Bioinformatics and Health Organization” by the Traditional Chinese Folk Medicine Research and Development Association, awarded the grant of sponsorship by the Innovation and Technology Fund from the Hong Kong government, our achievements not only can assist acupuncture to promote therapeutic effects to shorten the sufferings of patients, but also undoubtedly a gospel to the development of the academic community.

 

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